Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research

Single-cell RNA sequencing (scRNA-seq) revolutionized our understanding of disease biology. The promise it presents to also transform translational research requires highly standardized and robust software workflows. Here, we present the toolkit Besca, which streamlines scRNA-seq analyses and their...

Full description

Bibliographic Details
Main Authors:	Badi, L. (Author), Ebeling, M. (Author), Hatje, K. (Author), Julien-Laferriere, A. (Author), Kam-Thong, T. (Author), Kang, A.S.W (Author), Mädler, S.C (Author), Phan, M. (Author), Schmucki, R. (Author), Schwalie, P.C (Author), Sonrel, A. (Author), Ulrich, E. (Author), Wyss, L. (Author), Zhang, J.D (Author)
Format:	Article
Language:	English
Published:	Oxford University Press 2021
Subjects:	acinar cell animal cell Article automation B lymphocyte benchmarking blood cell bone marrow cell CD4+ T lymphocyte CD8+ T lymphocyte cell count cell function cell heterogeneity cell population classifier clustering algorithm colon epithelium colorectal cancer computer model controlled study controlled vocabulary cross validation cytology data analysis data classification data clustering data consistency data interoperability deconvolution algorithm diabetes mellitus ductal carcinoma endothelium cell enteroendocrine cell epithelium cell feature selection fibroblast gene expression profiling gene nomenclature gene ontology gene set analysis genetic database germinal center glia cell goblet cell hematopoietic cell hierarchical clustering human human cell inflammatory bowel disease information retrieval intestine cell intestine innervation lamina propria marker gene measurement accuracy memory cell memory T lymphocyte molecular genetics monocyte mouse nonhuman pancreas cancer pancreas cell pancreas islet pancreas islet beta cell pancreas tumor Paneth cell peripheral blood mononuclear cell plasma cell process optimization quality control regulatory T lymphocyte single cell RNA seq species difference standardization supervised machine learning support vector machine tissue characterization transcriptomics translational research ulcerative colitis vascular endothelial cell workflow
Online Access:	View Fulltext in Publisher

Internet

View Fulltext in Publisher

Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research

Internet

Similar Items