NaViA: A program for the visual analysis of complex mass spectra

Motivation: Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the sp...

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Bibliographic Details
Main Authors: Chen, S. (Author), Davis, R. (Author), Esser, T.K (Author), Fiorentino, F. (Author), Liko, I. (Author), Lovera, S. (Author), Newport, T.D (Author), Quetschlich, D. (Author), Robinson, C.V (Author), Shutin, D. (Author), Stansfeld, P.J (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Online Access:View Fulltext in Publisher
LEADER 01649nam a2200253Ia 4500
001 10.1093-bioinformatics-btab436
008 220427s2021 CNT 000 0 und d
020 |a 13674803 (ISSN) 
245 1 0 |a NaViA: A program for the visual analysis of complex mass spectra 
260 0 |b Oxford University Press  |c 2021 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1093/bioinformatics/btab436 
520 3 |a Motivation: Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the spectra obtained. These spectra can be time-consuming to tackle through manual assignment and challenging for automated approaches. Results: Native Mass Spectrometry Visual Analyser is a web-based tool to augment the manual process of peak assignment. In addition to matching masses to the stoichiometry of its component subunits, it allows raw data processing, assignment and annotation and permits mass spectra to be shared with their respective interpretation. © 2021 The Author(s) 2021. Published by Oxford University Press. 
700 1 |a Chen, S.  |e author 
700 1 |a Davis, R.  |e author 
700 1 |a Esser, T.K.  |e author 
700 1 |a Fiorentino, F.  |e author 
700 1 |a Liko, I.  |e author 
700 1 |a Lovera, S.  |e author 
700 1 |a Newport, T.D.  |e author 
700 1 |a Quetschlich, D.  |e author 
700 1 |a Robinson, C.V.  |e author 
700 1 |a Shutin, D.  |e author 
700 1 |a Stansfeld, P.J.  |e author 
773 |t Bioinformatics