CCmed: Cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression
Motivation: Trans-acting expression quantitative trait loci (eQTLs) collectively explain a substantial proportion of expression variation, yet are challenging to detect and replicate since their effects are often individually weak. A large proportion of genetic effects on distal genes are mediated t...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2021
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| Online Access: | View Fulltext in Publisher |