Oncogenic role and potential regulatory mechanism of topoisomerase IIα in a pan-cancer analysis

Topoisomerase IIα (TOP2A) plays an oncogenic role in multiple tumor types. However, no pan-cancer analysis about the function and the upstream molecular mechanism of TOP2A is available. For the first time, we analyzed potential oncogenic roles of TOP2A in 33 cancer types via The Cancer Genome Atlas...

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Bibliographic Details
Main Authors: Cai, Y. (Author), Gao, X. (Author), Lyu, L. (Author), Tang, B. (Author), Wang, J. (Author), Wang, X. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher