Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by an inappropriate host response to infection. The presence of oxidative stress and inflammatory mediators in sepsis leads to dysregulated gene expression, leading to a hyperinflammatory response. Environmental conditions play an impo...

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Bibliographic Details
Main Authors: Abatti, M. (Author), Borges, H. (Author), Córneo, E. (Author), da Silva Matos, N. (Author), Dal-Pizzol, F. (Author), Dominguini, D. (Author), Gabriel, F.F (Author), Gonçalves, R.C (Author), Goulart, A. (Author), Michels, M. (Author), Valvassori, S. (Author), Varela, R. (Author), Vieira, A. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher