Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia

Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common malignant hematological diseases in children. An immunosuppressive microenvironment, particularly regulatory T cell (Treg) infiltration, has been documented to be highly associated with childhood ALL. This present study, based on genetic factors,...

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Bibliographic Details
Main Authors: Fang, Y. (Author), Huang, J. (Author), Kang, M. (Author), Li, H. (Author), Ma, X. (Author), Sun, X. (Author), Wang, Y. (Author), Wu, Y. (Author), Xue, Y. (Author), Yang, X. (Author), Zhang, H. (Author), Zhu, Y. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Online Access:View Fulltext in Publisher

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