A beginner's guide to assembling a draft genome and analyzing structural variants with long-read sequencing technologies
Advances in long-read DNA sequencing technologies have enabled researchers to obtain high-quality genomes and finely resolve structural variants (SVs) in many species, even from small laboratories. The hands-on protocol presented here will guide you through the process of analyzing three different t...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cell Press
2022
|
| Subjects: | |
| Online Access: | View Fulltext in Publisher |
| Summary: | Advances in long-read DNA sequencing technologies have enabled researchers to obtain high-quality genomes and finely resolve structural variants (SVs) in many species, even from small laboratories. The hands-on protocol presented here will guide you through the process of analyzing three different types of publicly available Drosophila melanogaster datasets obtained using current long-read sequencing technologies. We hope that this protocol will help in guiding researchers who are new to the process of long-read sequencing analysis. © 2022 The Author(s) |
|---|---|
| ISBN: | 26661667 (ISSN) |
| DOI: | 10.1016/j.xpro.2022.101506 |