Constrained Optimization for Pneumococcal Vaccination in Brazil

Constrained Optimization for Pneumococcal Vaccination in Brazil

Objectives: To identify the most cost-efficient combination of pneumococcal vaccines in infants and aging adults for a 10-year period in Brazil. Methods: Constrained optimization (CO) prioritized 9 pneumococcal vaccine regimens according to their gain in quality-adjusted life-years (QALYs) and their...

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Bibliographic Details
Main Authors: Gomez, J.A (Author), Olbrecht, J. (Author), Standaert, B. (Author), Van Bellinghen, L.-A (Author), Van Vlaenderen, I. (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2021
Subjects:
adolescent
adult
Adult
aged
Article
Brazil
budget
child
cohort analysis
controlled study
cost effectiveness analysis
drug efficacy
economic evaluation
epidemiological data
Haemophilus influenzae vaccine
health care cost
herd immunity
high risk population
human
Humans
infant
Infant
investment
optimization
pneumococcal infection
Pneumococcal Infections
pneumococcal vaccination
Pneumococcal Vaccines
Pneumococcus vaccine
priority journal
process optimization
quality adjusted life year
scoring system
vaccination
Vaccination
vaccine
Vaccines, Conjugate
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