Prepubertal androgen signaling is required to establish male fat distribution

Fat distribution is sexually dimorphic and is associated with metabolic disease risk. It is unknown if prepubertal sex-hormone signaling influences adult fat distribution. Here, we show that karyotypically male androgen-insensitive mice exhibit pronounced subcutaneous adiposity compared with wild-ty...

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Bibliographic Details
Main Authors: Rodeheffer, M.S (Author), Sebo, Z.L (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
Online Access:View Fulltext in Publisher