Sleep deprivation induces corneal epithelial progenitor cell over-expansion through disruption of redox homeostasis in the tear film

Sleep deprivation induces corneal epithelial progenitor cell over-expansion through disruption of redox homeostasis in the tear film

Sleep deficiency, a common public health problem, causes ocular discomfort and affects ocular surface health. However, the underlying mechanism remains unclear. Herein, we identified that short-term sleep deprivation (SD) resulted in hyperproliferation of corneal epithelial progenitor cells (CEPCs)...

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Bibliographic Details
Main Authors: Anchouche, S. (Author), Hu, J. (Author), Li, D. (Author), Li, S. (Author), Li, W. (Author), Liu, Z. (Author), Tang, L. (Author), Wu, J. (Author), Yang, Y. (Author), Yin, J. (Author), Zhou, J. (Author), Zhou, Y. (Author)
Format: Article
Language:English
Published: Cell Press 2022
Subjects:
cell proliferation
cornea
dry eye
epithelial progenitor cell
lacrimal gland
limbal stem cell
ROS
sleep deprivation
stem cell
tear film
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