Oral microbiome in Proliferative Verrucous Leukoplakia exhibits loss of diversity and enrichment of pathogens

Oral microbiome in Proliferative Verrucous Leukoplakia exhibits loss of diversity and enrichment of pathogens

Objectives: Oral microbiome plays an important role in oral diseases. Among them, proliferative verrucous leucoplakia (PVL) is an uncommon form of progressive multifocal leukoplakia with a worryingly rate of malignant transformation. Here, we aimed to characterize the oral microbiome of PVL patients...

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Bibliographic Details
Main Authors:	Bagan, J. (Author), Bagan, L. (Author), Gallach, S. (Author), Herreros-Pomares, A. (Author), Jantus-Lewintre, E. (Author), Llorens, C. (Author), Murillo, J. (Author), Soriano, B. (Author), Zhang, F. (Author)
Format:	Article
Language:	English
Published:	Elsevier Ltd 2021
Subjects:	16S rRNA Actinobacteria adult aged Aggregatibacter Article Bacillus bacterium identification Bacteroidales Bacteroidetes biopsy Biopsy buccal mucosa Campylobacter Campylobacter jejuni cell transformation Cell Transformation, Neoplastic clinical article cohort analysis community structure comparative study controlled study Corynebacterium DNA dysplasia Eubacterium Exiguobacterium female Firmicutes Fusobacteria Fusobacterium genetics gingiva Granulicatella Haemophilus Head and neck cancer human human tissue Humans illumina sequencing infectious agent Leptotrichia leukoplakia Leukoplakia, Oral male microbial community microbial diversity microbiology Microbiota microflora Mobiluncus mouth Mouth mouth flora mucosa Mycoplasma oral biopsy Oral cancer Oral leukoplakia Oribacterium Pathogens Peptoniphilus Porphyromonas proliferative verrucous leukoplakia Proteobacteria real time polymerase chain reaction ribosome RNA RNA 16S RNA, Ribosomal, 16S Rothia Streptococcus Streptococcus agalactiae Tannerella taxon taxonomy Veillonella very elderly
Online Access:	View Fulltext in Publisher

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