A literature review on beneficial role of vitamins and trace elements: Evidence from published clinical studies

• Main Authors: Ali Abumalloh, R. (Author), Asadi, S. (Author), Ghabban, N.M.A (Author), Mohd Yusuf, S.Y (Author), Nilashi, M. (Author), Samad, S. (Author), Supriyanto, E. (Author), Taheri, S. (Author)
• Format: Article
• Language: English
• Published: Elsevier GmbH 2021
• Series: Journal of Trace Elements in Medicine and Biology
• Subjects: adult respiratory distress syndrome; alpha tocopherol; alpha tocopherol deficiency; antiviral activity; ascorbic acid; Bibliometric analysis; bibliometrics; Bibliometrics; ceruloplasmin; ceruloplasmin blood level; Chikungunya virus; chronic hepatitis B; clinical trial (topic); Clinical Trials as Topic; colecalciferol; copper; copper blood level; copper deficiency; coronavirus disease 2019; COVID-19; cyanocobalamin; dengue; diarrhea; drug effect; enzyme activity; epidemiology; gene expression; glutathione; human; Human immunodeficiency virus 1 infection; Human immunodeficiency virus infection; Humans; immune system; Immune system; Immune System; immunomodulation; infection risk; influenza; Influenza A virus (H1N1); innate immunity; lower respiratory tract infection; malaria; measles; Middle East respiratory syndrome coronavirus; morbidity; mortality; nicotinamide; nonhuman; pneumonia; protein blood level; pyridoxine; retinol; retinol deficiency; Review; Rhinovirus; SARS coronavirus; selenium; selenium deficiency; severe acute respiratory syndrome; superoxide dismutase; trace element; Trace elements; Trace Elements; transforming growth factor beta; virus infectivity; virus replication; vitamin; vitamin B deficiency; vitamin blood level; vitamin D; vitamin supplementation; Vitamins; Zika virus; zinc; zinc blood level; zinc deficiency
• Online Access: View Fulltext in Publisher; View in Scopus
• ISBN: 0946672X (ISSN)
• DOI: 10.1016/j.jtemb.2021.126789

COVID-19 is a kind of SARS-CoV-2 viral infectious pneumonia. This research aims to perform a bibliometric analysis of the published studies of vitamins and trace elements in the Scopus database with a special focus on COVID-19 disease. To achieve the goal of the study, network and density visualizations were used to introduce an overall picture of the published literature. Following the bibliometric analysis, we discuss the potential benefits of vitamins and trace elements on immune system function and COVID-19, supporting the discussion with evidence from published clinical studies. The previous studies show that D and A vitamins demonstrated a higher potential benefit, while Selenium, Copper, and Zinc were found to have favorable effects on immune modulation in viral respiratory infections among trace elements. The principles of nutrition from the findings of this research could be useful in preventing and treating COVID-19. © 2021 Elsevier GmbH