Formation mechanisms of sub-micron pharmaceutical composite particles derived from far- and near-field Raman microscopy

Formation mechanisms of sub-micron pharmaceutical composite particles derived from far- and near-field Raman microscopy

Surface enhanced Raman spectroscopy (SERS) and confocal Raman microscopy are applied to investigate the structure and the molecular arrangement of sub-micron furosemide and polyvinylpyrrolidone (furosemide/PVP) particles produced by spray flash evaporation (SFE). Morphology, size and crystallinity o...

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Bibliographic Details
Main Authors:	Busby, Y. (Author), Coty, J.-B (Author), Hübner, J. (Author), Spitzer, D. (Author)
Format:	Article
Language:	English
Published:	Xi'an Jiaotong University 2021
Subjects:	aerosol Article confocal microscopy Confocal Raman microscopy controlled study crystal structure evaporation furosemide microscopy nanocrystal particle size Pharmaceutic composites povidone Raman spectrometry scanning electron microscopy SERS silver Sub-micron particles Surface characterization surface enhanced Raman spectroscopy surface property X ray powder diffraction
Online Access:	View Fulltext in Publisher

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