ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis
Background/Objectives: Advanced thermoplastic materials, such as polyether-ether-ketone (PEEK) and highly cross-linked polyethylene (HXLPE), have been increasingly used as orthopaedic implant materials. Similar to other implants, PEEK-on-HXLPE prostheses produce debris from polymer wear that may act...
Main Authors: | Long, T. (Author), Lyu, Z. (Author), Meng, X. (Author), Wang, Y. (Author), Zhang, W. (Author) |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier (Singapore) Pte Ltd
2022
|
Subjects: | |
Online Access: | View Fulltext in Publisher |
Similar Items
-
Jatrorrhizine Hydrochloride Suppresses RANKL-Induced Osteoclastogenesis and Protects against Wear Particle-Induced Osteolysis
by: Hui Li, et al.
Published: (2018-11-01) -
Puerarin Exerts Protective Effects on Wear Particle-Induced Inflammatory Osteolysis
by: Chao Yang, et al.
Published: (2019-10-01) -
Evidence for Gender-Specific Bone Loss Mechanisms in Periprosthetic Osteolysis
by: Renee T. Ormsby, et al.
Published: (2019-12-01) -
Macrophage inhibits the osteogenesis of fibroblasts in ultrahigh molecular weight polyethylene (UHMWPE) wear particle-induced osteolysis
by: Pengfei Lei, et al.
Published: (2019-03-01) -
Phillyrin Attenuates Osteoclast Formation and Function and Prevents LPS-Induced Osteolysis in Mice
by: Jing Wang, et al.
Published: (2019-10-01)