ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis
Background/Objectives: Advanced thermoplastic materials, such as polyether-ether-ketone (PEEK) and highly cross-linked polyethylene (HXLPE), have been increasingly used as orthopaedic implant materials. Similar to other implants, PEEK-on-HXLPE prostheses produce debris from polymer wear that may act...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier (Singapore) Pte Ltd
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |