Characterizing the course of suicidal ideation response to ketamine

Background: : No pharmacological treatments exist for active suicidal ideation (SI), but the glutamatergic modulator ketamine elicits rapid changes in SI. We developed data-driven subgroups of SI trajectories after ketamine administration, then evaluated clinical, demographic, and neurobiological fa...

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Bibliographic Details
Main Authors:	Ballard, E.D (Author), Farmer, C.A (Author), Kadriu, B. (Author), Machado-Vieira, R. (Author), Niciu, M.J (Author), Park, L. (Author), Richards, E. (Author), Yarrington, J.S (Author), Yuan, P. (Author), Zarate, C.A., Jr (Author)
Format:	Article
Language:	English
Published:	Elsevier B.V. 2018
Subjects:	adult Adult amino acid receptor blocking agent Article automutilation Beck Depression Inventory biological marker bipolar depression bipolar disorder Bipolar Disorder bipolar I disorder bipolar II disorder crossover procedure Depression Depressive Disorder, Major Diagnostic and Statistical Manual of Mental Disorders disease course double blind procedure Excitatory Amino Acid Antagonists female Female gamma interferon Growth mixture modeling Hamilton Depression Rating Scale human Humans indoleamine 2,3 dioxygenase infusion interleukin 1 interleukin 10 interleukin 2 interleukin 5 interleukin 6 interleukin 8 ketamine Ketamine kynurenine kynurenine acid Logistic Models major clinical study major depression male Male middle aged Middle Aged Montgomery Asberg Depression Rating Scale neurotrophic factor priority journal protein blood level protein S100B Psychiatric Status Rating Scales psychological rating scale psychology psychopharmacotherapy quinolinic acid randomized controlled trial (topic) remission single drug dose statistical model suicidal ideation Suicidal ideation Suicidal Ideation suicide Suicide treatment response tumor necrosis factor tumor necrosis factor receptor 1 unclassified drug vasculotropin
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Characterizing the course of suicidal ideation response to ketamine

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