Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge

Background: Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time. Case presentation: We...

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Bibliographic Details
Main Authors: Jamarun, S.A (Author), Wong, E.H.C (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Online Access:View Fulltext in Publisher
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008 220510s2022 CNT 000 0 und d
020 |a 22102612 (ISSN) 
245 1 0 |a Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge 
260 0 |b Elsevier Ltd  |c 2022 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1016/j.ijscr.2022.107056 
520 3 |a Background: Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time. Case presentation: We described a 72-year-old gentleman who presented with left-sided nasal obstruction, rhinorrhoea and hyposmia and right-sided hearing loss. Examination revealed bilateral intranasal polyposis with right lobular swelling at torus tubarius and right sided middle ear effusion. Biopsy revealed inflammatory nasal polyps with nasopharyngeal amyloidosis. Patient was treated successfully with functional endoscopic sinus surgery (FESS) for nasal polyposis and an en bloc wide local excision of the torus tubarius with no signs of recurrence at one year follow-up. Conclusion: Clinicians should have raised index of suspicion of a possible primary nasopharyngeal amyloidosis in patients presenting with nasopharyngeal mass with co-existing nasal polyposis to avoid delay in diagnosis and treatment. © 2022 The Authors 
650 0 4 |a Amyloidosis 
650 0 4 |a Nasal 
650 0 4 |a Nasopharyngeal 
650 0 4 |a Polyposis 
700 1 |a Jamarun, S.A.  |e author 
700 1 |a Wong, E.H.C.  |e author 
773 |t International Journal of Surgery Case Reports