Huogu injection alleviates SONFH by regulating adipogenic differentiation of BMSCs via targeting the miR-34c-5p/MDM4 pathway

Huogu injection alleviates SONFH by regulating adipogenic differentiation of BMSCs via targeting the miR-34c-5p/MDM4 pathway

Although the precise pathogenesis of steroid-induced osteonecrosis of femoral head (SONFH) is not yet fully understood, evidence shows miRNAs-mediated posttranscription control directs the adipogenesis of bone marrow mesenchymal stem cells (BMSCs) and plays a pivotal role in the SONFH processes. Huo...

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Bibliographic Details
Main Authors: Hou, Y. (Author), Li, T. (Author), Li, X. (Author), Liu, Z. (Author), Lv, H. (Author), Song, T. (Author), Xu, X. (Author), Yang, F. (Author), Zhang, X. (Author), Zhao, J. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
Adipogenic differentiation
BSMCs
Huogu injection
miR-34c-5p/MDM4 pathway
SONFH
Online Access:View Fulltext in Publisher

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