Synthesis and structure–activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2
We previously discovered that triterpenoid saponin platycodin D inhibits the SARS-CoV-2 entry to the host cell. Herein, we synthesized various saponin derivatives and established a structure–activity relationship of saponin-based antiviral agents against SARS-CoV-2. We discovered that the C3-glucose...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Academic Press Inc.
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |