Smartphone mindfulness meditation training reduces Pro-inflammatory gene expression in stressed adults: A randomized controlled trial

Mindfulness meditation training has been shown to be an effective stress reduction strategy, but less is known about its immunoregulatory impact. In a randomized controlled trial of stressed customer service workers, the present study tested whether a 30-day smartphone-based mindfulness meditation t...

Full description

Bibliographic Details
Main Authors: Cole, S.W (Author), Creswell, J.D (Author), Dutcher, J.M (Author), Williams, A.C (Author)
Format: Article
Language:English
Published: Academic Press Inc. 2022
Subjects:
Online Access:View Fulltext in Publisher
LEADER 01657nam a2200217Ia 4500
001 10.1016-j.bbi.2022.04.003
008 220517s2022 CNT 000 0 und d
020 |a 08891591 (ISSN) 
245 1 0 |a Smartphone mindfulness meditation training reduces Pro-inflammatory gene expression in stressed adults: A randomized controlled trial 
260 0 |b Academic Press Inc.  |c 2022 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1016/j.bbi.2022.04.003 
520 3 |a Mindfulness meditation training has been shown to be an effective stress reduction strategy, but less is known about its immunoregulatory impact. In a randomized controlled trial of stressed customer service workers, the present study tested whether a 30-day smartphone-based mindfulness meditation training program (compared to a problem-solving control program) would affect pro-inflammatory gene expression. Both interventions led to reductions in stress levels, but there was no difference in stress reduction between conditions. Consistent with predictions, mindfulness training reduced activity of the pro-inflammatory NF-κB transcription control pathway compared to the active control. These results suggest that mindfulness training may be a particularly effective method for improving immune cell gene expression in stressful work environments. © 2022 The Author(s) 
650 0 4 |a Inflammatory gene expression 
650 0 4 |a Mindfulness 
650 0 4 |a Randomized controlled trial 
650 0 4 |a Stress 
700 1 |a Cole, S.W.  |e author 
700 1 |a Creswell, J.D.  |e author 
700 1 |a Dutcher, J.M.  |e author 
700 1 |a Williams, A.C.  |e author 
773 |t Brain, Behavior, and Immunity