Myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccination: A case report

• Main Authors: Kang, M.C (Author), Min, J.-H (Author), Oh, S.Y (Author), Park, K.-A (Author)
• Format: Article
• Language: English
• Published: Elsevier Inc. 2022
• Subjects: Antiacetylcholine receptor antibody; ChAdOx1 nCoV-19 vaccine; Corona virus disease-19; COVID-19; Myasthenia gravis with ocular symptoms
• Online Access: View Fulltext in Publisher
• ISBN: 24519936 (ISSN)
• DOI: 10.1016/j.ajoc.2022.101620

Purpose: We report on the case of a 35-year-old man who developed myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccine injection. Observations: A 35-year-old man complained of binocular diplopia one month following ChAdOx1 nCoV-19 vaccination. He had weak infraduction of the left eye. Upper and lower extremity strength was normal on presentation. A serum antiacetylcholine receptor antibody titer was elevated at 1.60 nmol/L. His diplopia improved temporarily following the application of an ice pack for 2 min. Conclusions and importance: This case report describes a rare occurrence of myasthenia gravis with ocular symptoms as a potential complication of ChAdOx1 nCoV-19 vaccination. © 2022 The Authors