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01584nam a2200229Ia 4500 |
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10.1007-s12064-021-00353-7 |
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220427s2021 CNT 000 0 und d |
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|a 14317613 (ISSN)
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245 |
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|a Geometry and symmetry in biochemical reaction systems
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260 |
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|b Springer Science and Business Media Deutschland GmbH
|c 2021
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|z View Fulltext in Publisher
|u https://doi.org/10.1007/s12064-021-00353-7
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|a Complex systems of intracellular biochemical reactions have a central role in regulating cell identities and functions. Biochemical reaction systems are typically studied using the language and tools of graph theory. However, graph representations only describe pairwise interactions between molecular species and so are not well suited to modelling complex sets of reactions that may involve numerous reactants and/or products. Here, we make use of a recently developed hypergraph theory of chemical reactions that naturally allows for higher-order interactions to explore the geometry and quantify functional redundancy in biochemical reactions systems. Our results constitute a general theory of automorphisms for oriented hypergraphs and describe the effect of automorphism group structure on hypergraph Laplacian spectra. © 2021, The Author(s).
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|a algorithm
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|a Algorithms
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|a Complex systems
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|a Hypergraphs
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|a Spectral properties
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|a Symmetry
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|a MacArthur, B.D.
|e author
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|a Mulas, R.
|e author
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|a Sánchez-García, R.J.
|e author
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773 |
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|t Theory in Biosciences
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