Directed evolution of the PobR allosteric transcription factor to generate a biosensor for 4-hydroxymandelic acid
Hydroxy-mandelic acid (HMA) is widely applied in pharmaceuticals, food and cosmetics. In this study, we aimed to develop an allosteric transcription factors (aTFs) based biosensor for HMA. PobR, an aTF for HMA analog 4-hydroxybenzoic acid, was used to alter its selectivity and create novel aTFs resp...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media B.V.
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |