Epidemiological differences of common liver conditions between Asia and the West

• Main Authors: Chan, W.-K (Author), Jayaraman, T. (Author), Lee, Y.-Y (Author), Mahadeva, S. (Author)
• Format: Article
• Language: English
• Published: John Wiley and Sons Inc., 2020
• Subjects: acetaminophen toxicity; acute liver failure; acute on chronic liver failure; acute-on-chronic liver failure; alcohol consumption; Asia; Child Pugh score; DNA polymorphism; drug-induced liver injury; epidemiology; hepatic encephalopathy; hepatocellular carcinoma; histology; human; immunization; liver cell carcinoma; liver disease; mortality rate; nonalcoholic fatty liver; non-alcoholic fatty liver disease; nuclear magnetic resonance spectroscopy; paracetamol; paracetamol induced hepatotoxicity; prevalence; priority journal; quality of life; Review; risk factor; socioeconomics; toxic hepatitis
• Online Access: View Fulltext in Publisher; View in Scopus
• ISBN: 23979070 (ISSN)
• ISSN: 23979070 (ISSN)
• DOI: 10.1002/jgh3.12275

Liver diseases form a heterogenous group of acute and chronic disorders of varying etiologies. Not only do they result in significant morbidity and mortality, but they also lead to a marked reduction in quality of life, together with a high socioeconomic burden globally. A better understanding of their global distribution is necessary to curb the massive health-care and socioeconomic burden that they entail. Notable differences and similarities have been described between common liver disease conditions occurring in Asia and the West (Europe and North America), giving rise to the need for an updated collective appraisal of this subject. In this review, the epidemiological differences of common liver conditions, specifically acute liver failure, drug-induced liver injury, acute-on-chronic liver failure, hepatocellular carcinoma, and non-alcoholic fatty liver disease, between Asia and the West are discussed. © 2019 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.