Relationship between regional gray matter volumes and dopamine D2 receptor and transporter in living human brains

Relationship between regional gray matter volumes and dopamine D2 receptor and transporter in living human brains

Although striatal dopamine neurotransmission is believed to be functionally linked to the formation of the corticostriatal network, there has been little evidence for this regulatory process in the human brain and its disruptions in neuropsychiatric disorders. Here, we aimed to investigate associati...

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Bibliographic Details
Main Authors: Fujiwara, H. (Author), Higuchi, M. (Author), Ito, H. (Author), Kimura, Y. (Author), Kubota, M. (Author), Kurose, S. (Author), Mimura, M. (Author), Suhara, T. (Author), Takahata, K. (Author), Takeuchi, H. (Author), Yamamoto, Y. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
Article
brain
corpus striatum
D2 receptor
diagnostic imaging
dopamine 2 receptor
Dopamine Plasma Membrane Transport Proteins
dopamine transporter
DRD2 protein, human
functional connectivity
gray matter
Gray Matter
gray matter volume
human
Humans
Magnetic Resonance Imaging
male
Male
metabolism
MRI
neostriatum
Neostriatum
nigroneostriatal system
normal human
nuclear magnetic resonance imaging
parahippocampal gyrus
pathology
PET
positron emission tomography
Positron-Emission Tomography
prefrontal cortex
Prefrontal Cortex
raclopride c 11
radioligand
radiopharmaceutical agent
Radiopharmaceuticals
Receptors, Dopamine D2
sensorimotor function
SLC6A3 protein, human
striatum
supplementary motor area
ventral striatum
Ventral Striatum
voxel based morphometry
young adult
Young Adult
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