Regulation of a Novel Splice Variant of Early Growth Response 4 (EGR4-S) by HER+ Signalling and HSF1 in Breast Cancer

Regulation of a Novel Splice Variant of Early Growth Response 4 (EGR4-S) by HER+ Signalling and HSF1 in Breast Cancer

The zinc finger transcription factor EGR4 has previously been identified as having a critical role in the proliferation of small cell lung cancer. Here, we have identified a novel, shortened splice variant of this transcription factor (EGR4-S) that is regulated by Heat Shock Factor-1 (HSF1). Our fin...

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Bibliographic Details
Main Authors: Bolton, J. (Author), Calderwood, S.K (Author), Dow, C.A (Author), Drake, J.M (Author), Guerrero-Gimenez, M.E (Author), Lang, B.J (Author), Nguyen, C.H (Author), Price, J.T (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Breast cancer
EGR4
HER2
HSF1
Molecular stress
Online Access:View Fulltext in Publisher

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