Psychotic Symptoms as the Initial Presentation of a Long-Lasting Misdiagnosed Anti-GAD65 Autoimmune Encephalitis: An Emblematic Case and Literature Review

Objective: To present a long-lasting misdiagnosed case of anti-GAD65 autoimmune encephalitis (AE) and promote the early identification of reversible psychotic symptoms in AE. Methods: The case report was generated through detailed assessment of clinical characteristics, cerebral magnetic resonance i...

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Bibliographic Details
Main Authors: Cai, D. (Author), Gong, S. (Author), Huang, B. (Author), Kong, F. (Author), Li, J. (Author), Lin, S. (Author), Wang, J. (Author), Zhang, T. (Author), Zheng, H. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
Online Access:View Fulltext in Publisher
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020 |a 16640640 (ISSN) 
245 1 0 |a Psychotic Symptoms as the Initial Presentation of a Long-Lasting Misdiagnosed Anti-GAD65 Autoimmune Encephalitis: An Emblematic Case and Literature Review 
260 0 |b Frontiers Media S.A.  |c 2022 
856 |z View Fulltext in Publisher  |u https://doi.org/10.3389/fpsyt.2022.754938 
520 3 |a Objective: To present a long-lasting misdiagnosed case of anti-GAD65 autoimmune encephalitis (AE) and promote the early identification of reversible psychotic symptoms in AE. Methods: The case report was generated through detailed assessment of clinical characteristics, cerebral magnetic resonance images, and laboratory results. Meanwhile, a literatures review related to the topic was conducted. Results: Psychotic symptoms could be presented in the early stage of anti-GAD65 autoimmune encephalitis. Even though there exists a transdisciplinary gap that hinder the timely recognition of early psychiatric symptoms as components of organic disease, a few strategies could be introduced to enable the earlier recognition and appropriate treatment. Conclusions: Our report intends to raise awareness to promote the early identification of immune-mediated “symptomatic” forms of psychosis. Copyright © 2022 Wang, Gong, Kong, Cai, Huang, Zheng, Lin, Li and Zhang. 
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700 1 0 |a Cai, D.  |e author 
700 1 0 |a Gong, S.  |e author 
700 1 0 |a Huang, B.  |e author 
700 1 0 |a Kong, F.  |e author 
700 1 0 |a Li, J.  |e author 
700 1 0 |a Lin, S.  |e author 
700 1 0 |a Wang, J.  |e author 
700 1 0 |a Zhang, T.  |e author 
700 1 0 |a Zheng, H.  |e author 
773 |t Frontiers in Psychiatry