Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA

Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA

Circulating cell-free DNA (cfDNA) can be used to characterize tumor genomes through next-generation sequencing (NGS)-based approaches. We aim to identify novel genetic alterations associated with drug resistance in lung cancer and colorectal cancer patients who were treated with EGFR-targeted therap...

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Bibliographic Details
Main Authors: Chang, W.J (Author), Choi, J. (Author), Choi, J.Y (Author), Kim, B. (Author), Kim, Y.H (Author), Lee, J.W (Author), Lee, S. (Author), Lee, S.B (Author), Lee, S.Y (Author), Park, Y.S (Author), Sung, J.S (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
circulating cell-free DNA (cfDNA)
colorectal cancer
drug resistance
lung cancer
whole exome sequencing
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