Celecoxib Colorectal Bioavailability and Chemopreventive Response in Patients with Familial Adenomatous Polyposis

Celecoxib Colorectal Bioavailability and Chemopreventive Response in Patients with Familial Adenomatous Polyposis

Why celecoxib exerts chemopreventive activity in only some familial adenomatous polyposis (FAP) patients remains poorly understood. We conducted a phase II clinical study to identify potential predictive biomarkers for celecoxib chemopreventive activity in FAP. Twenty-seven patients with FAP complet...

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Bibliographic Details
Main Authors:	Advani, S. (Author), Day, R.S (Author), Malek, J. (Author), Shureiqi, I. (Author), Wei, B. (Author), Yang, P. (Author), Zuo, X. (Author)
Format:	Article
Language:	English
Published:	NLM (Medline) 2022
Subjects:	Adenomatous Polyposis Coli bioavailability Biological Availability celecoxib Celecoxib colon polyposis human Humans pathology pyrazole derivative Pyrazoles sulfonamide Sulfonamides
Online Access:	View Fulltext in Publisher

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