Celecoxib Colorectal Bioavailability and Chemopreventive Response in Patients with Familial Adenomatous Polyposis

Why celecoxib exerts chemopreventive activity in only some familial adenomatous polyposis (FAP) patients remains poorly understood. We conducted a phase II clinical study to identify potential predictive biomarkers for celecoxib chemopreventive activity in FAP. Twenty-seven patients with FAP complet...

Full description

Bibliographic Details
Main Authors: Advani, S. (Author), Day, R.S (Author), Malek, J. (Author), Shureiqi, I. (Author), Wei, B. (Author), Yang, P. (Author), Zuo, X. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Online Access:View Fulltext in Publisher