Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma

Aberrant methylation of genomic DNA has been reported in many cancers. Specific DNA methylation patterns have been shown to provide clinically useful prognostic information and define molecular disease subtypes with different response to therapy and long-term outcome. Osteosarcoma is an aggressive m...

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Bibliographic Details
Main Authors: Aryee, M.J (Author), Choy, E. (Author), Cote, G.M (Author), Ebb, D.H (Author), Haibe-Kains, B. (Author), Kelly, A.D (Author), Lietz, C.E (Author), Lozano-Calderon, S.A (Author), Luscko, C.A (Author), Newman, E.T (Author), Nielsen, G.P (Author), Raskin, K.A (Author), Spentzos, D. (Author), Xiang, D.H (Author), Zhang, Z. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher