CBASS phage defense and evolution of antiviral nucleotide signaling

Cyclic oligonucleotide-based antiphage signaling system (CBASS) immunity is a widespread form of antiphage defense in bacteria and archaea. Each CBASS operon encodes a cGAS/DncV-like Nucleotidyltransferase (CD-NTase) enzyme that synthesizes a nucleotide second messenger in response to viral infectio...

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Bibliographic Details
Main Authors: Duncan-Lowey, B. (Author), Kranzusch, P.J (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Online Access:View Fulltext in Publisher