Chapter The Multiple Roles of Tyrosinase-Related Protein-2/L- Dopachrome Tautomerase in Melanoma: Biomarker, Therapeutic Target, and Molecular Driver in Tumor Progression
Cutaneous malignant melanoma (CMM), which is ranked as the 8th most common cancers in the US, makes 4-7% of skin cancers but it causes approximately 80% of skin cancer deaths. CMM is characterized by insidious and fast progression, heterogenic evolution, and significant resistance to numerous therap...
Main Author: | Negroiu, Gabriela (auth) |
---|---|
Other Authors: | Milac, Adina L. (auth) |
Format: | eBook |
Published: |
InTechOpen
2018
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Chapter The Multiple Roles of Tyrosinase-Related Protein-2/L- Dopachrome Tautomerase in Melanoma: Biomarker, Therapeutic Target, and Molecular Driver in Tumor Progression
Published: (2018) -
An Evolutionary Perspective of Dopachrome Tautomerase Enzymes in Metazoans
by: Umberto Rosani, et al.
Published: (2019-06-01) -
Decoding Melanoma Development and Progression: Identification of Therapeutic Vulnerabilities
by: Kevinn Eddy, et al.
Published: (2021-02-01) -
Macrophage Migration Inhibitory Factor (MIF) and Its Homologue d-Dopachrome Tautomerase (DDT) Inversely Correlate with Inflammation in Discoid Lupus Erythematosus
by: Rosario Caltabiano, et al.
Published: (2021-01-01) -
Identification of L-Cysteinamide as a Potent Inhibitor of Tyrosinase-Mediated Dopachrome Formation and Eumelanin Synthesis
by: Hyun Kyung Lee, et al.
Published: (2021-07-01)