Gene fusions in cancer: Classification of fusion events and regulation patterns of fusion pathway neighbors

Cancer is a leading cause of death worldwide, resulting in an estimated 1.6 million mortalities and 600,000 new cases in the US alone in 2015. Gene fusions, hybrid genes formed from two originally separated genes, are known drivers of cancer. However, gene fusions have also been found in healthy cel...

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Bibliographic Details
Main Author: Hughes, Katelyn
Other Authors: Dmitry Korkin, Advisor
Format: Others
Published: Digital WPI 2016
Subjects:
Online Access:https://digitalcommons.wpi.edu/etd-theses/764
https://digitalcommons.wpi.edu/cgi/viewcontent.cgi?article=1763&context=etd-theses