Design, Synthesis, and Evaluation of Bicyclic Peptides as Ammonium Ionophores

A series of bicyclic peptides have been designed and synthesized to provide ammonium ion complexation sites via hydrogen bonding in a tetrahedral geometry. Molecular modeling dynamics and electrostatics studies indicate that target compounds 1d-6d may provide better selectivity for ammonium ions ov...

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Bibliographic Details
Main Author: Nowak, Cheryl L
Other Authors: W. Grant McGimpsey, Advisor
Format: Others
Published: Digital WPI 2003
Subjects:
Online Access:https://digitalcommons.wpi.edu/etd-theses/434
https://digitalcommons.wpi.edu/cgi/viewcontent.cgi?article=1433&context=etd-theses