The Role of Integrins in Cellular Response to Mechanical Stimuli
Tissue cells exhibit varying responses according to the stiffness of their extracellular matrix (ECM). The mechanism of this stiffness sensing is not fully understood; however, it is known that cells probe stiffness by applying intracellular force to the ECM via integrin-mediated focal adhesions. Th...
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Digital WPI
2017
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| Online Access: | https://digitalcommons.wpi.edu/etd-theses/114 https://digitalcommons.wpi.edu/cgi/viewcontent.cgi?article=1113&context=etd-theses |