Cyclophilin A as a molecular switch regulating prolactin receptor mediated signaling, mammary tumorigenesis and metastasis
Prolactin (PRL) and its receptor (PRLr) have been implicated in the development and progression of human breast cancer. PRL activates its receptor and induces activation of proximal Janus kinase 2 (Jak2) for signal transduction. Here, we sought to determine the role of PRLr-associated peptidyl-pro...
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VCU Scholars Compass
2019
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| Online Access: | https://scholarscompass.vcu.edu/etd/6017 https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=7118&context=etd |