Epigenetic editing to validate findings from methylome-wide association studies of neuropsychiatric disorders

DNA methylation is necessary for learning, memory consolidation and has been implicated in a number of neuropsychiatric disorders. Obtaining high quality and comprehensive data for the three common forms of methylation in brain is challenging for methylome-wide association studies (MWAS). To address...

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Bibliographic Details
Main Author: Chan, Robin F.
Format: Others
Published: VCU Scholars Compass 2017
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/5003
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=6088&context=etd