Representativeness of Patients Enrolled in a Primary Care Clinical Trial for Substance Use Disorders

Understanding the characteristics of research participants is crucial to ensuring sample representativeness and generalizability of findings to broader patient groups with substance use disorders. Using anonymous computer-administered health survey data, the present study had a unique opportunity to...

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Bibliographic Details
Main Author: Kelpin, Sydney S
Format: Others
Published: VCU Scholars Compass 2016
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/4594
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5628&context=etd
Description
Summary:Understanding the characteristics of research participants is crucial to ensuring sample representativeness and generalizability of findings to broader patient groups with substance use disorders. Using anonymous computer-administered health survey data, the present study had a unique opportunity to compare patients who chose to participate in an RCT for heavy/problem drinking or drug use (N=713; consenters) with those that chose not to participate (N=625; non-consenters). The sample was 40% male, 76% African American, and had a mean age of 45.2 years. Using multivariate regression, the most parsimonious model found older age, unemployment, prescription misuse, positive screen for drug problems (CAGE), having a grandmother with an alcohol problem, trouble falling asleep (past 30 days), health professional recommendation to go on a diet, and feeling unsafe due to a previous partner were all associated with consenting to participate. The present study provides benchmark data on sample representativeness in a clinical trial of SBIRT.