Synthesis of Polyhydroxybenzene Derivatives for Evaluation as Antitumor Agents
In order to prepare more effective inhibitors of ribonucleotide reductase a series of 4-substituted and 4,5-disubstituted catechols were synthesized and tested. The derivatives synthesized were also examined for their antitumor activity against L1210 leukemia in mice. A free radical scavenging assay...
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| Format: | Others |
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VCU Scholars Compass
1986
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| Online Access: | http://scholarscompass.vcu.edu/etd/4380 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5441&context=etd |