Distribution of Imipramine, Desipramine and Their Principal Metabolites Between Plasma, Red Blood Cells and Brain in Humans and Animal Models
An HPLC prodecure was developed for the simultaneous measurement of imipramine (IMP), desipramine (DMI), desmethyl desipramine (DMD), 2-hydroxyimipramine (2HI) and 2-hydroxydesipramine (2HD) in human, rat and rabbit blood and brain specimens. The HPLC results were validated by comparison to an estab...
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| Format: | Others |
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VCU Scholars Compass
1983
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| Online Access: | http://scholarscompass.vcu.edu/etd/4357 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5421&context=etd |