Assembly and regulation of the DREAM complex
The DREAM complex assembles during G0/G1 when RB-like protein p130 recruits E2F4, DP1, and a core complex of five MuvB proteins to repress genes involved in cell cycle progression. In S-phase, the MuvB core dissociates from p130 and binds to BMYB transcription factor. Binding of the MuvB core to p13...
Main Author: | |
---|---|
Format: | Others |
Published: |
VCU Scholars Compass
2016
|
Subjects: | |
Online Access: | http://scholarscompass.vcu.edu/etd/4148 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=5168&context=etd |