Using structural analysis to investigate the function of Suppressor of IKK-epsilon (SIKE)

The innate immune system provides the body’s first line of defense against pathogenic challenge through pathogen recognition and initiation of the immune response. Among the various cellular mechanisms of pathogen recognition in mammals, Toll-like receptor 3 (TLR3) recognizes viral dsRNA. Stimulatio...

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Bibliographic Details
Main Author: McKinley, Sean W
Format: Others
Published: VCU Scholars Compass 2014
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/3670
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4695&context=etd