Regulation and Mechanistic Functions of Caspase-9 RNA Splicing

Caspase-9 has two splice variants, pro-apoptotic caspase-9a and anti-apoptotic caspase-9b, and dysregulation of caspase-9 splice variant ratio or expression of caspase-9b isoform has been linked to augmentation of the anchorage-independent growth and tumorigenic capacity of non-small cell lung cance...

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Bibliographic Details
Main Author: Vu, Ngoc T
Format: Others
Published: VCU Scholars Compass 2014
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/3578
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4582&context=etd