THE ROLE OF CYTOPROTECTIVE AND NON-PROTECTIVE AUTOPHAGY IN RADIATION SENSITIVITY IN BREAST TUMOR CELLS
In general, ionizing radiation promotes cytoprotective autophagy in a majority of breast tumor cells. Previous studies from our laboratory indicated that radiation (5x2 Gy) induces cytoprotective autophagy in MCF-7 cells. In the current work, inhibition of autophagy by silencing of Beclin-1 in MCF-7...
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| Format: | Others |
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VCU Scholars Compass
2014
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| Online Access: | http://scholarscompass.vcu.edu/etd/3425 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4424&context=etd |