Detecting and Correcting Batch Effects in High-Throughput Genomic Experiments

Batch effects are due to probe-specific systematic variation between groups of samples (batches) resulting from experimental features that are not of biological interest. Principal components analysis (PCA) is commonly used as a visual tool to determine whether batch effects exist after applying a g...

Full description

Bibliographic Details
Main Author: Reese, Sarah
Format: Others
Published: VCU Scholars Compass 2013
Subjects:
Online Access:http://scholarscompass.vcu.edu/etd/3180
http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4179&context=etd