Chemometric Analysis of Multivariate Liquid Chromatography Data: Applications in Pharmacokinetics, Metabolomics, and Toxicology
In the first part of this work, LC-MS data were used to calculate the in-vitro intrinsic clearances (CLint) for the metabolism of p-methoxyrnethamphetamine (PMMA) and fluoxetine by the CYP2D6 enzyme using a steady-state (SS) approach and a new general enzyme (GE) screening method. For PMMA, the SS e...
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| Format: | Others |
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VCU Scholars Compass
2006
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| Online Access: | http://scholarscompass.vcu.edu/etd/1156 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2155&context=etd |