Characterization and development of a stroke-induced model of acquired epilepsy in organotypic hippocampal slice cultures: role of the cannabinoid CB1 receptors in modulation of neuronal excitation and inhibition
Stroke is the most common cause of acquired epilepsy in persons 35 and older. The massive increase in extracellular glutamate during stroke causes a cascade of intracellular events that can lead to cell death or the molecular changes that initiate the development of epilepsy. In addition, many studi...
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VCU Scholars Compass
2010
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Online Access: | http://scholarscompass.vcu.edu/etd/145 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1144&context=etd |