Characterization Of A Non-Canonical Function For Threonyl-Trna Synthetase In Angiogenesis
In addition to its canonical role in aminoacylation, threonyl-tRNA synthetase (TARS) possesses pro-angiogenic activity that is susceptible to the TARS-specific antibiotic borrelidin. However, the therapeutic benefit of borrelidin is offset by its strong toxicity to living cells. The removal of a sin...
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| Format: | Others |
| Language: | en |
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ScholarWorks @ UVM
2015
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| Online Access: | http://scholarworks.uvm.edu/graddis/523 http://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=1522&context=graddis |