Expression and purification of HIV-I TAT protein transduction domain fused with acid β-glucosidase and enhanced green fluorescent protein
The protein transduction domain (PTD) of the HIV-I TAT protein has been shown to be capable of crossing cellular membranes and even the blood-brain barrier while carrying cargo molecules along with it. Exploiting this property to deliver biologically active acid β-glucosidase (GBA) would be of use t...
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2008
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| Online Access: | http://hdl.handle.net/1828/469 |